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Space-Based 3D Cell Culture Research Paves the Way for New Cancer Therapies

In October, we think pink, and for a good reason—one out of every eight women will be diagnosed with breast cancer in their lifetime, and each year, 2 million women are given this frightening diagnosis.

Biotechnology startup MicroQuin leveraged the International Space Station (ISS) National Laboratory to grow 3D breast and prostate cancer cell cultures to learn more about how these cancers develop and grow. However, the research team found something incredible that could lead to a way to treat not just breast and prostate cancers but all cancers.

Research suggests heart condition impacted by many rather than one single gene

Dilated cardiomyopathy (DCM) affects the heart’s ability to efficiently pump blood, as the organ grows larger but weaker.

It had been thought that the cause was faulty copies of one single gene inherited down family lines. However, in more cases than not, no specific gene can be identified as faulty.

Now a new study in Nature Genetics journal suggests that as much as one third of the risk is attributable to the cumulative but individually small effects of many thousands of genetic differences.

Capturing the Complexity of Real Cancer Cases with Patient-Derived Xenograft Models

One of the most significant areas of advancement in oncology is the growing capacity to match patients with therapies tailored to their unique cancer. As more relevant biomarkers and druggable targets are identified, drug developers still face an evergreen challenge: narrowing down the most promising therapeutic candidate from hundreds of compounds is akin to looking for a needle in a haystack. Relevant preclinical models are vital to ensuring that time and money are invested in advancing the most effective drug candidates.

While traditional cell line-derived xenograft (CDX) models generated with established cancer cell lines are a valuable tool for initially assessing the efficacy of experimental drugs, these models fall short in capturing the intricacies of patients’ actual clinical situations.