Based on the mechanism of the piston-shaft spring, Mechanical micropipettes are operated manually. They are great when pipetting a moderate number of samples.
In an electronic pipette, the piston is motor-driven. Using an electronic pipette allows one to dispense precisely how it was programmed due to the motor control that allows the piston movement to be controlled. Also, Electronic micropipettes are available both as single-channel and multi-channel micropipettes. Volume adjustment can be done electronically and the adjusted volume is shown digitally on the digital readout.